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Indication and time of liver transplant
Basically, when no efficient internal medical measures is available for any kind of acute or chronic liver disease, the patient is estimated to be devitalized in short term (6~12 months); and the living quality is severely influenced by the liver disease, liver transplantation is indicated. such as,
| adult |
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child |
| liver cirrhosis |
|
biliary atresia |
| primary biliary cirrhosis |
hereditary metabolic disease |
| sclerotic cholangitis |
liver cirrhosis due to any causes |
| primary malignant tumor |
familial biliary stasis |
| fulminant liver failure |
hereditary fibrotic disease |
| Budd-Chiari syndrome |
|
| secondary biliary cirrhosis |
It's very difficult to set unified optimal operation time for liver transplantation, but, if the operation is undertaken too late, transplant risk will be increased, even severalfold; If too early, it's possible to deprive some of the patients' chance to recover without transplant, therefore, the time parameters for transplant that are currently widely accepted are as following,
when such symptoms occur as following, liver transplant should be taken immediately
one or several kind of complications related to portal hypertension or liver failure
repeated esophageal-stomach hemorrhage
refractory ascites
liver encephalopathy
severe coagulation dysfunction
repeated voluntary peritonitis
liver-kidney syndrome
severe sopor, refractory itch, severe metabolic osteopathia, repeated choliangitis
LAB FINGDINGS,
albumin<25g/l
PT 5s than normal
TBIL>50mg/l
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